RESUMO
OBJECTIVE: To investigate the application value and safety of NIPPV (noninvasive positive pressure ventilation) combined with routine clearance in elderly patients with stroke-associated pneumonia (SAP). METHODS: Altogether 88 elderly SAP patients treated in our hospital from January 2021 to January 2022 were retrospectively evaluated. Among them, 48 cases treated with NIPPV and routine clearance were regarded as an experimental group (EG), and 40 with routine clearance alone were enrolled to a control group (CG). The sputum clearance rate and CPIS score were compared. The safety of NIPPV was evaluated. The clearance treatment cost, hospitalization time and expenses, and the changes of inflammatory factors (IL-6, TNF-α, C-reactive protein (CRP)) were compared before and after treatment. The efficacy of airway clearance after treatment and the risk factors affecting the severity of infection was assessed. RESULTS: The sputum clearance rate in the EG was higher than that in the CG (P < 0.05). After treatment, the CPIS score of EG was lower (P < 0.05). The hospitalization time and expenses of CG were higher. After treatment, the serum inflammatory factors in CG were higher (P < 0.05), while the clinical efficacy of EG was higher (P < 0.05). Treatment plan, course of disease and diabetes are risk factors for postoperative infection. CONCLUSION: NIPPV combined with routine clearance is effective for elderly SAP patients, which can shorten the hospitalization time and reduce the expenses.
RESUMO
BACKGROUND: To our knowledge, only 1 study has investigated the effects of kinesio taping (KT) on pulmonary function and functional capacity of patients with chronic obstructive pulmonary disease (COPD). Therefore, there is still a lack of high-quality evidence to prove the effectiveness of KT for COPD patients. Our purpose was to investigate the effect of KT on respiratory function and muscle strength in the COPD patients who were in stable condition. METHODS: This research project has been received ethical approval from the Medical Research and Ethics Committee in Affiliated Nanhua Hospital, University of South China. This work is a part of a comprehensive research project to assess and provide intervention that potentially improves respiratory function and quality of life among patients with COPD. Participants recruited into the study need to fulfill the following criteria: clinical diagnosis of COPD and symptoms indicative of exacerbation; spontaneous breathing on hospital admission; and physiotherapy since the first day of hospitalization. Patients will be assigned at random to the COPD medical treatment + KT (Group 1), or the COPD medical treatment alone (Group 2). The outcome measures are pulmonary function and respiratory muscle strength. The level of statistical significance is set as Pâ<â.05. RESULTS: This protocol will provide a reliable theoretical basis for the following research. CONCLUSIONS: It was hypothesized that thoracic KT could significantly change pulmonary function and functional capacity in patients with COPD. TRIAL REGISTRATION: This study protocol was registered in Research Registry (researchregistry6632).
